Uji Efektivitas Antibakteri Ekstrak Daun Ketapang (Terminalia catappa) dalam Menghambat Bakteri Escherichia coli

Abstract

Ketapang is one of the many medicinal plants that grows in Indonesia and has been used traditionally to treat various diseases such as skin diseases, breathing, digestive disorders and bacterial infections in the reproductive organs. Ketapang is known to contain medicinal compounds such as flavonoids, triterpenoids, tannins, alkaloids and steroids. Ketapang leaf extract is expected to inhibit the growth of Eschericia coli bacteria. The study was conducted experimentally with qualitative methods. Testing of Ketapang leaf extract against E. coli was done in vitro. The research data obtained were analyzed with Factorial Complete Randomized Design with 2 factors, namely location and extract concentration. The results showed that the extract of Ketapang leaves from Medan and Binjai with variations in extract concentrations of 25%, 50%, 75%, and 100% were known to be able to inhibit the growth of E.coli with varying inhibitory zone values. The largest clear zone diameter is found in extracts with a concentration of 50% from ketapang leaves from Medan City, while the ketapang leaves from Binjai City. The largest clear zone diameter is shown in extracts with a concentration of 100%.