The Effect of The Shift Work System on Function Enzymes which are Characterized by Increased Levels of SGOT and SGPT in The Blood of Workers at The Aluminium Smelting Plant, PT Inalum (Persero) Kuala Tanjung in 2017

Abstract

This study was conducted to measure the effect of the shift work system on liver dysfunction characterized by elevated of liver function enzymes SGOT (Serum Glutamic Oxaloacetic Transminase) and SGPT (Serum Glutamic Pyruvate Transaminase) in the employees of the PT Inalum (Persero) Kuala Tanjung smelting plant. The research method was descriptive which derived from primary and secondary data. Primary data is a direct examination of the levels of SGOT and SGPT liver function enzymes which are expressed in Unit units per liter of blood serum (U/L) which was the result of periodic examinations of two period employees who were examined by the Inalum Health Center Laboratory. Whereas secondary data came from PT Inalum (Persero) section of the Smelter Public Relations which is part of the Public Relations and Smelter Administration and Wal fare which is part of staffing to obtain employee work shift schedules. The data obtained were analyzed using paired t-test data analysis techniques by comparing the results of SGOT and SGPT enzymes between 324 shift and non-shift workers. The results showed that there were significant differences in SGOT and SGPT values average for 162 employees with shift work from the average SGOT Period I value of 34.4 U/L rising to 42.0 U/L in period II and the average SGPT value for the Period I is 62.5 U/L to 73.4 U/L in period II. While the average SGOT and SGPT values for 162 non-shift employees also increased, but still within normal limits, namely SGOT is < 35 U/L and SGPT < 45 U/L. Employees with a shift work system experienced an elevated of SGOT and SGPT levels which resulted impact on liver dysfunction caused by fatigue and lack of rest time. Whereas non-shift employees experienced an elevated of SGOT and SGPT levels but did not affect liver dysfunction.