Please use this identifier to cite or link to this item: https://repositori.uma.ac.id/handle/123456789/29383
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dc.contributor.advisorRahmati-
dc.contributor.authorSumbayak, Trivana-
dc.date.accessioned2026-02-10T02:09:12Z-
dc.date.available2026-02-10T02:09:12Z-
dc.date.issued2025-09-08-
dc.identifier.urihttps://repositori.uma.ac.id/handle/123456789/29383-
dc.description62 Halamanen_US
dc.description.abstractSenduduk merupakan tumbuhan liar yang mampu beradaptasi pada kondisi lingkungan yang kurang baik seperti tanah yang gersang, dan daerah yang panas. Tumbuhan senduduk mengandung senyawa metabolit sekunder golongan alkaloid, steroid, tanin, flavonoid dan saponin, yang berpotensi sebagai antibakteri. Tujuan dalam penelitian ini mengetahui potensi ekstrak etanol daun senduduk (Melastoma malabathricum L.) terhadap aktivitas antibakterri Escherichia coli, Helicobacter pylori dan Vibrio cholera. Jenis penelitian ini bersifat eksperimental laboratorium dengan metode difusi cakram yang dilakukan secara in vitro di laboratorium. Konsentraksi ekstrak yang digunakan adalah 25%, 50%, 75% dan 100%. Kontrol posistif yang digunakan berupa antibiotik kloramfenikol sedangkan kontrol negatif menggunakan DMSO. Hasil pengujian menunjukkan bahwa Estrak etanol daun senduduk memiliki aktivitas antibakteri terhadap H. pylori, E. coli dan V. cholerae dengan ditandai terbentuknya zona bening diarea kertas cakram. Berdasarkan ketiga bakteri tersebut yang paling efektif menghambat pertumbuhan bakteri patogen yaitu terhadap E.coli dengan nilai zona hambat yang paling besar pada kosentrasi 100% rata-rata 21,85 mm terkategori kuat. Senduduk is a wild plant that can adapt to poor environmental conditions such as arid soil and hot areas. Senduduk plants contain secondary metabolites such as alkaloids, steroids, tannins, flavonoids, and saponins, which have antibacterial potential. The objective of this study is to determine the potential of ethanol extracts from senduduk leaves (Melastoma malabathricum L.) against the antibacterial activity of Escherichia coli, Helicobacter pylori, and Vibrio cholera. This study is an experimental laboratory study using the disk diffusion method conducted in vitro in the laboratory. The concentrations of the extract used were 25%, 50%, 75%, and 100%. The positive control used was the antibiotic chloramphenicol, while the negative control used DMSO. The test results showed that the ethanol extract of senduduk leaves exhibited antibacterial activity against H. pylori, E. coli, and V. cholerae, as indicated by the formation of clear zones in the disk area. Among the three bacteria, the most effective in inhibiting the growth of pathogenic bacteria was against E. coli, with the largest inhibition zone at a concentration of 100%, averaging 21.85 mm, categorized as strong.en_US
dc.language.isoiden_US
dc.publisherUniversitas Medan Areaen_US
dc.relation.ispartofseriesNPM;218700006-
dc.subjectAntibacterialen_US
dc.subjectDaun Senduduken_US
dc.subjectDisc diffusionen_US
dc.subjectZona Hambaten_US
dc.subjectAntibakterien_US
dc.subjectDaun Senduduken_US
dc.subjectDifusi cakramen_US
dc.subjectZona Hambaten_US
dc.titleUji Aktivitas Antibakteri Ekstrak Etanol Daun Senduduk (Melastoma malabathricum L.)en_US
dc.title.alternativeAntibacterial Activity Test of Ethanol Extract of Senduduk Leaves (Melastoma malabathricum L.)en_US
dc.typeThesisen_US
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