Uji Efektifitas Ekstrak Etil Asetat Buah Andaliman (Zanthoxylum acanthopodium) dalam Menghambat Pertumbuhan Escherichia coli dan Staphylococcus aureus

Abstract

Andaliman (Zanthoxylum acanthopodium) is one of the wild plant that usually grows in nothern Sumatera, Indonesia. Batak people use the fruit as spices in their traditional cuisine like Arsik and Naniura. Chemical content of andaliman fruit such as flavonoids, alkaloids, saponins and terpenoids are useful for health. This study aimed to observed the effect of andaliman on the growth of Escherichia coli and Staphylococcus aureus. Parameters measured was the diameter of inhibitory zones in 24-hour incubation period. Extraction was conducted by using maceration method and the solvent used was ethyl acetate. The extract concentration consists 20%, 40%, 60% and 80% and 0% as a control. Based on the data andaliman extract significantly inhibited Escherichia coli and Staphylococcus aureus growth (P<0.01). The largest inhibition zone 12,6 mm of Escherichia coli and 13 mm of Staphylococcus aureus revealed in the cocentration of 80%.